Grand Rounds Recap 05.26.2021


Morbidity and Mortality WITH Dr. Koehler

Case 1: Flexor tenosynovitis

  • Kanavel’s Signs

    • Sausage digit

    • Pain to palpation along flexor tendon sheath

    • Held in passive flexion

    • Pain with passive extension

    • Case series showed 91-97% sensitivity and 51-69% specificity

    • Pain with passive extension and pain along tendon sheath have high sensitivity

  • Ultrasound can be used to assess for FTS

    • 94% sensitivity

    • 74% specificity

    • 97% negative predictive value

  • Risk factors for a poor outcome include:

    • Age > 43

    • Diabetes

    • Peripheral vascular disease

    • Renal disease

Case 2: Agonal Respirations in Cardiac Arrest

  • Gasping/agonal respirations is a brainstem reflex

    • Technically the patient not brain dead if they are having agonal respirations

  • This be very distressing to providers and family

  • Gasping respirations occur in 40% OHCA

    • OR 3.9 of 1 year survival in patients gasping during CPR

    • OR 57 to survival if patients have gasping respirations and a shockable rhythm

Case 3: Hyponatremia  

  • Serum osmolality and volume status are important considerations

    • Urine electrolytes can be helpful in hypovolemic patients, especially prior to fluid resuscitation

  • Severe hyponatremia is Na <120

    • Difference in US and European guidelines

      • European guidelines recommend hypertonic with:

        • Vomiting, confusion, headache

      • US guidelines recommend hypertonic with:

        • Self induced hyponatremia, post-op, intracranial pathology

      • Both guidelines recommend hypertonic with:

        • Seizures and coma

  • Chronicity is important

    • Acute hyponatremia occurs in under than 48 hours

      • Should be corrected quickly due to increased risk of herniation

      • Correct sodium by 4-6 meq/L

      • Hypertonic

        • 100ml q10 min

        • 1-2 ml/kg/hr infusion

    • Chronic hyponatremia occurs over 48 hours

      • Risk of osmotic demyelination syndrome in patients with:

        • Na < 105 

        • Hypokalemia

        • Alcohol use disorder, malnutrition, liver disease

      • Correct by 4-8 meq/L per day

        • Max 10-12 over 24 hours

        • Up to 18 over 48 hours

  • Hypovolemic hyponatremia

    • Use a balanced isotonic fluid

  • Hypervolemic hyponatremia

    • Fluid restriction

Case 4: Community Acquired Pneumonia

  • Ohio has approximately 43% of population vaccinated for Covid-19

    • Moderna has a 94.1% efficacy

    • Pfizer has 95% efficacy

    • Epic can show us if patients have received their vaccination under immunizations (check rarely used section)

  • CAP Guidelines were updated in October 2019

    • “Signs and symptoms of pneumonia with radiographic confirmation”

    • Guidelines do not apply for patients with immunocompromised conditions

    • Do we obtain a sputum culture?

      • No - for routine outpatient treatment

      • Yes - if empirically treated for MRSA, pseudomonas

    • Do we obtain a blood culture?

      • No - for routine out or inpatients

      • Yes - for severe CAP, empiric MRSA or pseudomonas treatment

    • Do we obtain flu testing?

      • Yes- when it is flu season

    • Inpatient vs outpatient disposition?

      • PSI (pneumonia severity index) preferred over Curb-65

  • CAP Treatment outpatient

    • Healthy patient 

      • 1g of amoxicillin TID

      • 100mg doxy BID

      • Macrolide if local resistance is <25%

    • Patient with comorbidities

      • Augmentin plus macrolide or doxy

      • Respiratory fluoroquinolone

  • CAP Treatment for inpatients

    • B-lactam plus macrolide

    • OR Respiratory fluoroquinolone

    • Risk factors for MRSA or pseudomonas

      • Prior isolate - cover immediately

      • <90 day hospitalization and exposure to abx

        • Wait for cultures unless severe PNA

Case 5: Volume Overload and ESRD

  • 86% of ESRD patients on dialysis had HTN

  • 75% of ESRD patients will develop LVH

    • Cardiovascular disease accounts for 40% of mortality

  • Emergent dialysis

    • Acidosis, electrolytes, intoxicants, overload volume, uremia (AEIOU)

  • How to temporize patients prior to dialysis?

    • If still producing urine, give 120mg IV lasix

    • Manage BP

      • Nitroglycerin may be the best medicine

        • Relaxes smooth muscles of vasculature

        • Venodilate, decreased preload and afterload, increases cardiac output

    • BiPap

      • Especially if there is respiratory distress

        • Recruits alveoli

        • Decreases respiratory effort

        • Increases intrathoracic pressure

      • Consider their mental status


Case 6: Antibiotics in Pancreatitis and Hypertriglyceridemia Pancreatitis

  • Royal College of Surgeons did a review and recommends no routine antibiotics in uncomplicated pancreatitis

    • Recommends antibiotics in severe increased white count or overt sepsis

  • AGA has similar recommendations

  • Hypertriglyceridemia pancreatitis

    • High rate of ICU, SIRS, organ failure 

    • Treatment is different

      • Insulin drip, PLEX

    • Can cause hyponatremia

    • Should we get triglycerides in the ED?

      • No clear recommendation in literature

      • However, it may change disposition and results in real time


Case 7: Excellent Patient Care in the ED

  • An excellent resuscitation of massive upper GI bleed involving transfusions, medical management of upper GI bleed, delayed sequence intubation, Minnesota tube, and MICU admission

  • Patient had a good outcome

  • Keep it up!


ABEM Residency Visitation Program Lecture WITH Dr. Kowalenko

  • ABEM was the 23rd recognized medical specialty

  • 38,544 active ABEM Diplomates

    • 93% EM residency graduates

    • 7% applied through the practice pathway

    • 7.6% also hold a subspeciality certificate

  • Covid-19 changed oral exams, please stay tuned for updates

  • ABEM is introducing a new way to stay certified called MyEMCert


Presidential Assassinations: A Medical History WITH Dr. Kowalenko

Abraham Lincoln

  • Suffered a GSW to the head

  • First responder was a: 24 year old Army Surgeon named Charles Augustus Leale

    • Removed clot from head wound to relieve pressure

    • Extended 2 fingers into airway to open airway

  • Emergency Care included:

    • Head to toe inspection

    • Wound was probed

    • Recleared the clot from head wound intermittently

      • Lincoln was bradycardic overnight, with episodes of normal heart rate as they intermittently cleared the clot from the wound

  • LIkely a fatal wound even in today’s standard of care

  • Critique of care: probed wound with nonsterile fingers/instruments (Lister theory of antisepsis was not widely accepted until 1880s)

James Garfield

  • Suffered a GSW to the back on July 2nd 1881

    • Dr. Smith Townsend arrived in four minutes

    • President was vomiting, fainting, dark red blood oozing from back

    • Tachycardic with feeble pulse, diaphoretic

    • Wound “2.5 inch to right of lumbar vertebra”

    • Sticks his finger into the wound to assess wound

  • Transferred to White House at 10am but was not undressed until 530pm

    • Receives morphine, atropine, water, milk, limewater, and cracked ice

    • Vomits every half hour and complains of pain in legs and numbness to arms

    • At 7pm, Naval Surgeon Wales reexamines the wound with his finger

      • Concludes it passed through liver and rests in abdominal cavity

  • Over next 2 days, several physicians probe the wound

  • Multiple physicians are recruited including Dr. Agnew from Philadelphia

  • President Garfield appeared to improve throughout next 2 weeks. However, on July 23rd he:

    • Develops vomiting and Fever and chills

    • Abscess discovered 3 inches below wound

    • Cleaned wound with 2% carbolic acid and potassium permanganate

    • Dr. Agnew lances abscess and inserts drain

  • July 26: Agnew enlarges incision and removes 1 inch piece of bone

    • Still cannot find bullet

  • July 26 and 31: Alexander Graham Bell and Newcomb attempt to find bullet

    • ‘Induction balance’, similar to a metal detector

    • 4.5 inches to the right of naval

  • August 8: Agnew explores 12 inches of wound track into pelvis. Garfield receives ether for the first time

  • Starts improving, but then August 18 develops parotitis and cannot tolerate PO

    • Receives nutrient enemas (egg, bouillon whiskey, paregoric)

  • President Garfield realizes he is decompensating, requests to leave DC and wants to go to the Jersey Shore

  • September 13 - mucopurulent sputum, pustules on back, chest pain, hallucinations

  • September 19 - complained of chest pain and pronounced dead shortly afterwards

  • Critique of care: not exposed for hours, no documented neuro exam, repeated nonsterile introduction of fingers and instruments to wound

William McKinley

  • Suffered GSWs to the abdomen

  • Ambulance arrives shortly afterwards

    • Dr. George Hall arrives with two medical students

    • Undressed the president, one bullet falls to the floor

    • Dr. Hall cleansed wound with antiseptic solution

    • Nurse gives morphine and strychnine

    • Dr. Mynter, surgeon, arrives shortly afterwards

    • However, Dr. Mann was chosen to be the physician to operate on the president. He was an ObGyn

  • Buffalo General Hospital was deemed too far away, it was decided they will operate at the small Hospital with a pocket set of OR instruments

    • Surgeons scrubbed with soap, water, mercuric chloride solution

    • Shave and scrubbed McKinley’s abdomen

    • Given ether so they cannot use gaslights, they attempted to assemble a mirror to reflect sunlight into the field of operation

    • Spilled stomach contents into peritoneal cavity

  • Post op next morning - president was tachycardic so he receives clysis fluid of extract and digitalis, he receives nutrient enemas

  • Next day he has no issues defecating and urinating

  • Has begins to have a good recovery but then a few days later he has tachycardia again and eventually passes away 8 days post-op

  • Autopsy showed necrosis of stomach, pancreas, retroperitoneum extending to kidney. 

  • Review of care: large body habitus, poor lighting, inadequate instruments, no evidence to support emergent operation (could have gone to bigger hospital), post op complications due to Mann’s lack of expertise

John F Kennedy

  • Suffered GSW to lower neck and head

    • One shot puts bullet through back of neck and penetrated trachea

    • Another shot strikes the right occiput. Fatal wound

  • Arrives to Parkland Hospital in 4 minutes

  • Trauma room one, assessed by general surgery resident Dr. James Carrico

    • Slow agonal respirations, intermittent heart beats, no palpable pulse or BP, unresponsive

    • Carriico creates tracheostomy site at level of wound, passes ETT through tracheal injury

    • Venous cutdowns, receives LR, placed on vent, administered 300mg solucortef (hx of addisons) IV, chest compressions begin

  • Dr. Bashout, cardiology, arrives and determines monitor showed no cardiac activity

  • Dr. Clark neurosurgeon arrives and pronounces him dead

  • Review of care: ABCs done well, secondary was poor since there were undiscovered wounds