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CSF Evaluation in Subarachnoid Hemorrhage
Diagnostics, Grand Rounds Timothy Murphy, MD Diagnostics, Grand Rounds Timothy Murphy, MD

CSF Evaluation in Subarachnoid Hemorrhage

So, what constitutes a “positive” tap when evaluating for subarachnoid hemorrhage?

Traditional teaching is that a positive tap is Xanthochromia or blood in the CSF

What exactly is Xanthochromia?

The word xanthochromia is simply Greek for “yellow color.”  It refers to the yellow color that CSF can take in certain situations.  Some of these situations are listed below:

  • Elevated CSF protein            
  • Jaundice
  • Hypervitaminosis A
  • Rifampin Therapy
  • Elevated Bilirubin
  • Oxyhemoglobin

What we are especially interested in when evaluating for subarachnoid hemorrhage is bilirubin and oxyhemoglobin.

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Respiratory Monitoring - An Introduction to Pulse Ox and Capnography
Diagnostics, Grand Rounds Jeffery Hill, MD M.Ed Diagnostics, Grand Rounds Jeffery Hill, MD M.Ed

Respiratory Monitoring - An Introduction to Pulse Ox and Capnography

First a bit of physics....

Both pulse oximetry and capnometry rely on the Beer-Lambert Law. 

  • In 1760, Johann Heinreich Lambert proved that the absorbance of light through a material is proportional to the thickness of the material.  
  • In 1852, August Beer proved that the absorbance of light through a material is proportional to the concentration of the attenuating substance in the material.
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What is Useful in the ED to Help Diagnose or Rule Out Septic Arthritis?
Grand Rounds, Diagnostics James Summers, MD Grand Rounds, Diagnostics James Summers, MD

What is Useful in the ED to Help Diagnose or Rule Out Septic Arthritis?

History

There are many risk factors for septic arthritis including age >80, Diabetes, Rheumatoid Arthritis, recent joint surgery, prosthesis, cellulitis.  The absence of risk factors does not make septic arthritis less likely in an acute monoarticular arthritis

Physical

Monoarticular arthritis is often characterized as a warm, painful, swollen joint with limited range of motion.  No studies to date have quantified specificity data on the physical exam.  Therefore, clinicians must use their own clinical gestalt when interpreting physical exam findings.

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